Graduating in 1937, he worked as a Senior House Officer at Harrogate Hospital, moving on to work as a ships surgeon. Returning from this post, he worked at Torbay Hospital before joining the Royal Army Medial Corps. In this post he served in India and the Middle East, reaching the rank of Major.
After the war, Imrie joined with Dr. Venn-Dunn in General Practice in Torquay, now the medical centre at St. Marys. He was also clinical assistant in the Geriatric department at Paignton Hospital, and Newton Abbot Hospital. He was involved in founding Lily Derry Day Hospital at Torbay, and was medical officer to both the Post Office and the Territorial Army.